The USB port doesn’t work. My PC doesn’t detect the EG21-GL module on my custom PCB

Hello, I designed a custom PCB based on the Quectel EG21-GL for the company I work for. I received the prototype board today and everything is working fine except for the USB interface. When I plug in the USB cable, the board powers up but my computer does not recognize the EG21—nothing appears in the Device Manager. I removed the TVS diode to test if that was the issue, but the problem persists. I’ve attached the schematic below.

Does the EG21 power on successfully?
Please check the VDD_EXT and the pwrkey.

hello yes it power suucsuflu i have lte network and mqtt working but usb dosnt work!
pwrkey it tight to ground
image|690x296

Please refer to Quectel’s hardware design manual to check for interference and whether the USB can be recognized when connected to other hosts.